Your combat effectiveness in Once Human hinges on your gear and weapon selection. A well-coordinated build is essential, whether you're battling corrupted creatures in PvE or assaulting player settlements in PvP, determining whether you survive or face a fresh start.
This guide details four of the strongest builds in the current version of Once Human, providing comprehensive information on weapons, gear modifications, synergy effects, and tactical advice. From area-of-effect clearing builds to damage-over-time and critical burst setups, each loadout has been rigorously tested for both solo and group play.
New players should refer to our Beginner's Guide for a complete introduction to Once Human.
Final Tips for Optimizing Your Build
Synchronize weapon effects and mods: Select equipment that directly amplifies your weapon's elemental or status effects.Continuous upgrades: Rarity and enhancement levels significantly increase performance—avoid using outdated gear.Prepare alternative loadouts: Maintaining a secondary build focused on a different element allows you to adapt to various mutant types or PvP counters.
Each build in Once Human is designed to excel in specific situations, be it boss encounters, clearing waves of enemies, or securing quick PvP eliminations. Test each loadout, adjust your gear modifications, and switch builds according to mission objectives or enemy vulnerabilities.
For an optimal gaming experience—featuring responsive aiming, efficient multi-instance farming, and swift inventory management—play Once Human on BlueStacks. Enhance your performance with comprehensive control support and exceptionally smooth frame rates.
